Senior Manager / Site Director, Clinical Operations

Join Us in Shaping the Future of Clinical Research Adams Clinical is a leading clinical trial site network committed to accelerating the development of life-changing medicines. Our mission is simple: deliver uncompromising data quality, safety, and diverse enrollment to advance healthcare. Our vision is to set the gold standard for clinical trial excellence. We believe our people make the difference. Guided by our core values— Scientific Rigor, Operational Excellence, Commitment to Sponsors and Participants, and Authentic Collaboration —we create an environment where meaningful work drives meaningful change. At Adams Clinical, you’ll find: A culture of respect, transparency, and continuous improvement Opportunities for professional growth and learning A team dedicated to improving lives through innovation and integrity If you’re passionate about making an impact in clinical research and want to be part of a collaborative, mission-driven organization, we’d love to have you on our team. Job Role The Senior Manager provides site-level leadership and operational ownership of clinical operations, with direct responsibility for staff management, study execution, regulatory compliance, strategic alignment with network leadership, and ensuring high-quality trial execution that meets sponsor expectations and business objectives. The Site Director assumes the same core clinical operations responsibilities while providing broader site-wide leadership through additional support of the Clinical Science function, clinician development, cross-functional performance, and integration of clinical science with site operations in partnership with Clinical Science leadership. This is a highly people-focused leadership role requiring strong interpersonal skills, professional discretion and effective decision-making, and the ability to lead and develop employees at all levels of the organization. The ideal candidate is an approachable and accountable leader who builds strong relationships, communicates with clarity, and creates a culture of trust, collaboration, and high performance while maintaining clear expectations for site operations. Key Responsibilities: Study Operations and Site Performance Serve as primary point of contact for day-to-day site issues; monitor study activities, enrollment, visit schedules, and site performance metrics for outpatient studies. Support subject recruitment, eligibility assessments, randomization, and oversee study processes including ALCOA-compliant documentation, study trackers, investigational product handling, and ensure proper handling of participant safety events and adverse events (e.g., SAE/AESI reporting). Identify operational, regulatory, or safety risks, implement mitigation strategies with senior leadership, and escalate critical issues. Collaborate with Finance to review Clinical Trial Agreement (CTA) invoicing, oversee participant reimbursement processes, and support site-level budget monitoring and forecasting to ensure financial compliance and operational efficiency. Review monthly P&L and present to network senior leadership monthly on prior month performance. Monitor screening outcomes and screen-failure trends related to operationally preventable factors to identify recurring issues and work with site study teams and Clinical Operations leadership to implement process improvements that improve overall screening quality. Exercise appropriate autonomy in day-to-day site decisions while escalating matters that require network-level alignment, senior leadership input, or clinical or medical expertise. Team Management and Development Foster a collaborative and accountable site culture by effectively navigating employee concerns, conflict, and performance issues; advocating for staff while balancing organizational expectations; and translating leadership priorities into clear, practical expectations for the team. Lead, train, and develop the Clinical Research Coordinators (CRCs), Research Assistants (RAs), and Laboratory Technicians; assign responsibilities and track staff involvement across studies. Wo