Senior Manager, IT Operations - Pleasanton, CA

Calyxo, Inc. is a medical device company headquartered in Pleasanton, California, USA. The company was founded in 2016 to address the profound need for improved kidney stone treatment. Kidney stone disease is a common, painful condition that consumes vast amounts of healthcare resources each year. Our team is led by executives and investors with a proven track record of commercializing paradigm-shifting devices to meet unmet needs within urology. Are you ready to change the future of kidney stone treatment? We are seeking high achievers who want to be part of a dynamic team working in a fun, diverse atmosphere. Summary : Calyxo is seeking an experienced Senior Manager, IT Operations to own the infrastructure backbone of the company as we scale toward and through IPO. This role leads day-to-day IT operations, ensuring reliable, secure, and responsive technology services that support Calyxo’s employees and business objectives . You will own our enterprise network and endpoint infrastructure — including switching, firewall , and wireless environments — and will be the operational lead for our core security tooling stack (endpoint detection and response, security awareness training, and endpoint/cloud security). You will also establish company-wide software license tracking, author and maintain IT policies and procedures, and own SOX testing and evidence management for IT general controls as Calyxo builds a public-company-grade control environment. As the team scales, this role will eventually take on oversight of the helpdesk/end-user support function. This is a foundational, build-oriented role — you will inherit a growing environment and be responsible for hardening it, documenting it, and scaling it to support a ~500-employee, pre-IPO medical device company. In This Role, You Will : Network & Infrastructure Operations Own the design, deployment, and ongoing administration of Calyxo’s network infrastructure, including enterprise-grade switches, firewalls, and wireless access points across HQ and manufacturing sites. Monitor network performance, capacity, and uptime; troubleshoot and resolve complex connectivity, routing, and security issues. Lead infrastructure and network build-out for new and expanding facilities (e.g., the Rosewood manufacturing site), including physical security and building management system integration. Maintain server, storage, and cloud infrastructure supporting business operations, in partnership with the broader IT team. Security Operations & Tooling Serve as the operational owner of Calyxo’s core security tooling stack, including security awareness training and phishing simulation, endpoint detection and response (EDR), and endpoint/cloud security platforms. Monitor security alerts and incidents, drive remediation, and continuously improve the company’s security posture. Partner with leadership to define and enforce security policies, access controls, and incident response procedures. Software Asset & License Management Establish and maintain a company-wide software license tracking process, ensuring accurate visibility into license counts, utilization , renewals, and compliance.